Also, SSRIs have very different molecular structures. Zoloft (Sertraline hydrochloride) was the second SSRI to come to market in the United States, and it was approved by the FDA in December 30, 1991. Paxil (Paroxetine hydrochloride) was the third SSRI to come to market in the United States and was approved by the FDA in December 29, 1992. Chemical structure of Paroxetine differs from other SSRIs by having a piperidine ring.
The first drug in the SSRI class was Prozac (Fluoxetine), which hit the United States market in 1987. Luvox (Fluvoxamine maleate) was the next SSRI FDA approved in December 05, 1994.
Low levels of serotonin and norepinephrine have not been proven to cause depression but it is widely believed that elevation of these chemicals is associated with improvement in mood in depressed people.
All selective serotonin reuptake inhibitors have the same principal mechanism of action.
Celexa is manufactured by Forest Pharmaceuticals, Inc.
Certain differences between SSRIs are clinically significant.Lexapro is manufactured by Forest Pharmaceuticals, Inc. Neurotransmitters carry signals from one nerve cell to another.Research suggests that abnormalities in neurotransmitter activity can affect mood and behavior.A sedative is anything that makes you sedate — peaceful, calm, tranquil.In medicine this word refers to drugs that relieve anxiety or tranquilizers that pretty much knock you out.