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Throughout the late 1800s and early 1900s, numerous businesses and stores were established, including the Franklin Automobile Company, which produced the first air-cooled engine in the world; the Century Motor Vehicle Company; the Smith Corona company; and the Craftsman Workshops, the center of Gustav Stickley's handmade furniture empire. It is now known as Upstate Medical University, one of four medical colleges in the State University of New York system, and one of only five medical schools in the state north of New York City.
On March 24, 1870, Syracuse University was founded.
Today, Syracuse is at the intersection of Interstates 81 and 90. Syracuse is home to Syracuse University, a major research university, as well as Le Moyne College, a nationally recognized liberal arts college.
Marie de Gannentaha, on the northeast shore of Onondaga Lake.
Jesuit missionaries reported salty brine springs around the southern end of what they referred to as "Salt Lake", known today as Onondaga Lake in honor of the historic tribe.
The village was called Solvay to commemorate the inventor, Ernest Solvay.
In 1861, he developed the ammonia-soda process for the manufacture of soda ash (anhydrous sodium carbonate, a rare chemical called nitrite, to distinguish it from natural natron of antiquity) from brine wells dug in the southern end of Tully valley (as a source of sodium chloride) and limestone (as a source of calcium carbonate).